What kind of documentation do I get with my oligonucleotides?
For DNA oligos in single tube format
The label on the oligo tube shows basic information like oligo name,
name of person who ordered, oligo sequence including modifications,
oligo ID, amount of DNA (OD260 and nmol), Tm, and molecular weight.
In addition, you will receive a synthesis report containing more
detailed information on the physical-chemical properties of the oligo,
such as base composition, base count, purification grade, amount of DNA
(OD260 and nmol), Tm and molecular weight. If you have
ordered HPLC purification or your ordered oligo is HPLC purified by
default (e.g. Dual labeled oligos, dual modified oligos, mid- and large scale oligos), you will also get a printout of the preparative chromatogram.
While each and every oligo produced and delivered is characterized by either MALDI- or ESI-ToF before release, Mass-Check documentation/spectra will only be provided if requested at time of order placement. Additional charges may apply. The following terminology is used for differentiating between offered QC options including respective documentation coverage in our order forms and on supporting documents delivered with the products:
Mass Check
Standard quality control performed on each and every oligo. Either
MALDI- or ESI-ToF, subject to the "nature of the oligo", and metabion
internal procedures. This service is free of charge and no printout/PDF
documentation is provided.
MALDI-ToF
Explicitly ordered and performed MALDI-ToF check. Product delivered with MALDI-ToF spectra. Additional charges apply.
ESI-ToF
Explicitly ordered and performed ESI-ToF check. Product delivered with ESI-ToF spectra. Additional charges apply.
Mass Check + Analytical HPLC
Explicitly ordered and performed Mass Check (MALDI-ToF or ESI-ToF
subject to the "nature of the oligo" and metabion internal procedures)
and Analytical HPLC (see FAQ "What is the difference between preparative and analytical HPLC?"). Product delivered with analytical HPLC and MS spectra. Additional charges apply.
For antisense/PTO oligos
The label on the antisense/PTO tube shows basic information like oligo name, name of person who ordered, antisense oligo sequence including modifications, oligo ID, amount of DNA (OD260 and nmol), Tm, and molecular weight.
In addition, you will receive a synthesis report containing more detailed information on the physical-chemical properties of the oligo, such as base composition, base count, purification grade, amount of DNA in nmol, Tm and molecular weight. Antisense DNA/PTOs are HPLC purified by default and you will also get a printout of the preparative chromatogram.
While each and every oligo produced and delivered is characterized by either MALDI- or ESI-ToF before release, Mass-Check documentation/spectra will only be provided if requested at time of order placement. Additional charges apply.
The following terminology is used for differentiating between offered QC options including respective documentation coverage in our order forms and on supporting documents delivered with the products:
Mass Check
Standard quality control performed on each and every oligo. Either MALDI- or
ESI-ToF, subject to the "nature of the oligo", and metabion internal
procedures. This service is free of charge and no printout/PDF documentation is
provided.
MALDI-ToF
Explicitly ordered and performed MALDI-ToF check. Product delivered with
MALDI-ToF spectra. Additional charges apply.
ESI-ToF
Explicitly ordered and performed ESI-ToF check. Product delivered with ESI-ToF spectra. Additional charges apply.
For ngs oligos
The label on the oligo tube shows basic information like oligo name, name of person who ordered, oligo sequence including modifications, oligo ID, amount of DNA (OD260 and nmol), Tm, and molecular weight.
In addition, you will receive a technical data sheet containing more detailed information on the physical-chemical properties of the oligo, such as base composition, base count, purification grade, amount of DNA (OD260 and nmol), Tm and molecular weight. You will also get a printout of the Mass-Check documentation/spectrum.
The following terminology is used for differentiating between offered QC options including respective documentation coverage in our order forms and on supporting documents delivered with the products:
Mass Check
Standard quality control performed on each and every oligo. Either MALDI- or ESI-ToF, subject to the "nature of the oligo", and metabion internal procedures. This service is free of charge and no printed/pdf documentation is provided. nGS oligos are always delivered with mass check spectra.
Mass Check + Analytical HPLC
Explicitly ordered and performed Mass Check (MALDI-ToF or ESI-ToF subject to the "nature of the oligo" and metabion internal procedures) and Analytical HPLC (see FAQ "What is the difference between preparative and analytical HPLC?"). Product delivered with analytical HPLC and MS spectra. Additional charges apply.
For DNA/RNA DLPs
The label on the DLP tube shows basic information like oligo name, name of person who ordered, DLP sequence including modifications, oligo ID, amount of DNA (OD260 and nmol), Tm, and molecular weight.
In addition, you will receive a synthesis report containing more detailed information on the physical-chemical properties of the oligo, such as base composition, base count, purification grade, amount of DNA (OD260 and nmol), Tm and molecular weight. DLPs are HPLC purified by default and you will also get a printout of the preparative chromatogram. Additionally, you will receive a hard copy of the mass check spectrum.
The following terminology is used for differentiating between offered QC options including respective documentation coverage in our order forms and on supporting documents delivered with the products:
Mass Check
Standard quality control performed on each and every oligo. Either
MALDI- or ESI-ToF, subject to the "nature of the oligo", and metabion
internal procedures. This service is free of charge and you will receive
a hard copy of the Mass Check spectrum.
Mass Check + Analytical HPLC
Explicitly ordered and performed Mass Check (MALDI-ToF or ESI-ToF
subject to the "nature of the oligo" and metabion internal procedures)
and Analytical HPLC (see FAQ "What is the difference between preparative and analytical HPLC?"). Product delivered with analytical HPLC and MS spectra. Additional charges apply.
For DQP/LNA/MGB probes
A hardcopy of the preparative HPLC chromatogram and the mass spectrum are included in addition to the respective synthesis report and delivery note.
For LC® probes
The label on the probe tube shows basic information like oligo name, name of person who ordered, probe sequence including modifications, probe ID, amount of DNA (OD260 and nmol), Tm, and molecular weight.
In addition, you will receive a synthesis report containing more detailed information on the physical-chemical properties of the oligo, such as base composition, base count, purification grade, amount of DNA (OD260 and nmol), Tm and molecular weight. LC®probes are always HPLC purified and you will also get a printout of the preparative chromatogram.
The following terminology is used for differentiating between offered QC options including respective documentation coverage in our order forms and on supporting documents delivered with the products:
Mass Check
Standard quality control performed on each and every oligo. Either
MALDI- or ESI-ToF, subject to the "nature of the oligo", and metabion
internal procedures. This service is free of charge and you will receive
a hard copy of the Mass Check spectrum.
Mass Check + Analytical HPLC
Explicitly ordered and performed Mass Check (MALDI-ToF or ESI-ToF
subject to the "nature of the oligo" and metabion internal procedures)
and Analytical HPLC (see FAQ "What is the difference between preparative and analytical HPLC?"). Product delivered with analytical HPLC and MS spectra. Additional charges apply.
For ZNA primers and probes
On the tube label you will find basic information such as oligo name, name of the person who placed the order, oligo sequence including modifications, oligo ID, delivered quantity of DNA and molecular weight.
In addition, you will receive a technical data sheet including more detailed information on physico-chemical properties of the oligo like base composition, GC-content, synthesis scale, purification grade, quality control information, etc. You will also receive a printout of the Mass-Check, free of charge.
For dsDNA/duplex DNA
The label on the dsDNA/duplex DNA tube shows basic information like oligo name, name of person who ordered, DLP sequence including modifications, oligo ID, amount of DNA (OD260 and nmol), Tm, and molecular weight.
In addition, you will receive a synthesis report containing more detailed information on the physical-chemical properties of the ssDNA oligo, such as base composition, base count, purification grade, amount of DNA (OD260 and nmol), Tm and molecular weight. dsDNA/duplex DNAs are HPLC purified by default and you will also get a printout of the preparative chromatogram.
While each and every oligo produced and delivered is characterized by either MALDI- or ESI-ToF before release. Mass-Check documentation/spectra will only be provided if requested at time of order placement. Additional charges may apply.
For RNA oligos
The label on the oligo tube shows basic information like oligo name, name of person who ordered, oligo sequence including modifications, oligo ID, amount of RNA (OD260 and nmol), Tm, and molecular weight.
In addition, you will receive a synthesis report containing more
detailed information on the physical-chemical properties of the oligo,
such as base composition, base count, purification grade, amount of RNA
(OD260 and nmol), Tm and molecular weight.
Each and every
oligo produced and delivered is analyzed by either MALDI- or ESI-ToF
before release, and Mass-Check documentation/spectra will be provided
upon additional charges (desalted RNA) or free of charge (HPLC purified
RNA). The following terminology is used for differentiating between
offered QC:
For desalted RNA:
Mass Check
Standard quality control performed on
each and every oligo. Either MALDI- or ESI-ToF, subject to the "nature
of the oligo", and metabion internal procedures. This service is free of
charge and no printed/pdf documentation is provided.
MALDI-ToF
Explicitly ordered and performed MALDI-ToF check. Product delivered with MALDI-ToF spectra. Additional charges apply.
ESI-ToF
Explicitly ordered and performed ESI-ToF check. Product delivered with ESI-ToF spectra. Additional charges apply.
Analytical HPLC
Performed Mass Check and Analytical HPLC (see FAQ "What is the difference between preparative and analytical HPLC?"). Product delivered with analytical HPLC but without MS spectra. Additional charges apply.
Mass Check + Analytical HPLC
Explicitly ordered
and performed Mass Check (MALDI-ToF or ESI-ToF subject to the "nature of
the oligo" and metabion internal procedures) and Analytical HPLC (see
FAQ "What is the difference between preparative and analytical HPLC?"). Product delivered with analytical HPLC and MS spectra. Additional charges apply.
For HPLC purified RNA:
Mass Check
Standard quality control performed on
each and every oligo. Either MALDI- or ESI-ToF, subject to the "nature
of the oligo", and metabion internal procedures. This service is free of
charge and will always be delivered with hard copies of the Mass Check
spectrum for all our HPLC purified RNA products.
Analytical HPLC
Mass Check (MALDI-ToF or ESI-ToF
subject to the "nature of the oligo" and metabion internal procedures)
and explicitly ordered Analytical HPLC (see FAQ "What is the difference between preparative and analytical HPLC?"). Product delivered with analytical HPLC and MS spectra. Additional charges apply.
For RNA Longmers
The label on the oligo tube shows basic information like oligo name, name of person who ordered, oligo sequence including modifications, oligo ID, amount of RNA (OD260 and nmol), Tm, and molecular weight.
In addition, you will receive a synthesis report containing more
detailed information on the physical-chemical properties of the oligo,
such as base composition, base count, purification grade, amount of RNA
(OD260 and nmol), Tm and molecular weight.
Each and every oligo produced and delivered is analyzed by either MALDI-
or ESI-ToF before release, and Mass-Check documentation/spectra will be
provided upon additional charges (desalted RNA) or free of charge (HPLC
purified RNA). The following terminology is used for differentiating
between offered QC:
For desalted RNA:
Mass Check
Standard quality control performed on each and every oligo. Either
MALDI- or ESI-ToF, subject to the "nature of the oligo", and metabion
internal procedures. This service is free of charge and no printed/pdf
documentation is provided.
MALDI-ToF
Explicitly ordered and performed MALDI-ToF check. Product delivered with a MALDI-ToF spectrum. Additional charges apply.
ESI-ToF
Explicitly ordered and performed ESI-ToF check. Product delivered with an ESI-ToF spectrum. Additional charges apply.
Analytical HPLC
Performed Mass Check and Analytical HPLC (see FAQ "What is the difference between preparative and analytical HPLC?"). Product delivered with analytical HPLC but without MS spectra. Additional charges apply.
Mass Check + Analytical HPLC
Explicitly ordered and performed Mass Check (MALDI-ToF or ESI-ToF
subject to the "nature of the oligo" and metabion internal procedures)
and Analytical HPLC (see FAQ "What is the difference between preparative and analytical HPLC?"). Product delivered with analytical HPLC and MS spectra. Additional charges apply.
For HPLC purified RNA:
Mass Check
Standard quality control performed on each and every oligo. Either
MALDI- or ESI-ToF, subject to the "nature of the oligo", and metabion
internal procedures. This service is free of charge and will always be
delivered with hard copies of the Mass Check spectrum for all our HPLC
purified RNA products.
Analytical HPLC
Mass Check (MALDI-ToF or ESI-ToF subject to the "nature of the oligo"
and metabion internal procedures) and explicitly ordered Analytical HPLC
(please read FAQ "What is the difference between preparative and analytical HPLC?"). Product delivered with analytical HPLC and MS spectra. Additional charges apply.
For siRNA/RNAi/duplex RNA
The label on the siRNA tube shows basic information like oligo name, name of person who placed the order, siRNA sequence including modifications, oligo ID, amount of RNA (OD260 and nmol), Tm, and molecular weight.
In addition, you will receive a technical data sheet containing more detailed information on the physical-chemical properties of the oligo, such as base composition, base count, purification grade, amount of RNA in nmol, Tm and molecular weight. Additionally, you will also receive a hard copy of the Mass-Check documentation/spectrum of each single strand of the duplex. The following terminology is used for differentiating between offered QC options including respective documentation coverage in our order forms and on supporting documents delivered with the products:
Mass Check
Standard quality control performed on each and every oligo. Either MALDI- or
ESI-ToF, subject to the "nature of the oligo", and metabion internal
procedures. This service is free of charge and the Mass Check spectrum will be
provided.
MALDI-ToF
Explicitly ordered and performed MALDI-ToF check. Product delivered with
MALDI-ToF spectra. Additional charges apply.
ESI-ToF
Explicitly ordered and performed ESI-ToF check. Product delivered with ESI-ToF spectra. Additional charges apply.
For MTP oligos
The label on the oligo plate shows basic information like name of person who ordered, name of the plate and order ID.
In addition, you will receive a synthesis report containing more detailed information, such as name of the oligos, physical-chemical properties of the oligos, such base composition, base count, purification grade, amount of DNA (OD260 and nmol), Tm and molecular weight.
While each and every oligo produced and delivered is characterized by either MALDI- or ESI-ToF before release, Mass-Check documentation/spectra will only be provided if requested at the time of order placement. Additional charges may apply. The following terminology is used for differentiating between offered QC options including respective documentation coverage in our order forms and on supporting documents delivered with the products:
Mass Check
Standard quality control performed on each and every oligo. Either
MALDI- or ESI-ToF, subject to the "nature of the oligo", and metabion
internal procedures. This service is free of charge and no printed/pdf
documentation is provided.
MALDI-ToF
Explicitly ordered and performed MALDI-ToF check. Product delivered with MALDI-ToF spectra. Additional charges apply.
ESI-ToF
Explicitly ordered and performed ESI-ToF check. Product delivered with ESI-ToF spectra. Additional charges apply.
Mass Check + Analytical HPLC
Explicitly ordered and performed Mass Check (MALDI-ToF or ESI-ToF
subject to the "nature of the oligo" and metabion internal procedures)
and Analytical High Pressure Liquid Chromatography (see FAQ "What is the difference between preparative and analytical HPLC?"). Product delivered with analytical HPLC and MS spectra. Additional charges apply.