Amine modifiers are employed to incorporate a primary amine group (NH2) into an oligonucleotides (Figure 1).
This modification allows for subsequent post-synthesis conjugation of the oligonucleotide with a variety of different moieties, like fluorescent dyes, quenchers, haptens, etc.
Figure 1. Structure of C2-Amino-dT (R = sequence).
metabion offers C2-Amino-dT as an internal modification in its standard DNA portfolio: