5-Bromo deoxyuridine (5-Br-dU) is a halogenated nucleotide, commonly used in X-ray crystallography to facilitate the determination of DNA structure. Additionally, they are photo-labile and therefore suitable for UV-crosslinking experiments to study protein-DNA complexes. 5-Br-dU was also used to create photo-aptamers able to crosslink with their target.

ModifiedBasis bromo dU

Metabion offers the modification in its DNA and RNA portfolio. Click here

MW 369.1 g/mol
Extinction coefficient (260 nm) 5.1 mM-1cm-1


W. Hendrickson, C. Ogata. Phase determination from multiwavelength anomalous diffraction measurements. Meth. Enzymol. (1997), 276: 494-523.

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