Inverted dT can be introduced at the 3’-end of an oligonucleotide to create a 3’-3’ linkage that stops DNA polymerase from further extending the DNA sequence. Additionally, inverted dT protects the oligonucleotide from 3’ exonuclease cleavage.

ModifiedBasis inverted dT

Metabion offers inverted-dT in its DNA portfolio. Click here

MW 304 g/mol
Extinction coefficient (260 nm) 8.4 mM-1cm-1

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